Homogenisation


The difference between homogenisation and stirring is often misunderstood.

Stirring is generally used for low viscosity samples (like water), when solids are to be distributed within a liquid or liquids are to be mixed. Stirring is done at relatively low speed and does not impact or change the nature of the sample by itself.

Homogenisation happens at much higher rotor speed. It is generally used to reduce material size (e.g. cut plant samples into a solvent for analysis) or to mix liquids with limited solubility (liquids that do not normally mix well) such as oil-in-water or two different oils, for example cannabis extract oil into MCT. Homogenisation can generate emulsions and ensures best possible product uniformity – ensuring accurate dosing.

Kinematica offers a range of Swiss made homogenisation solutions covering small volume R&D, scale up and pharmaceutical production. Production tools are cGMP compliant and suitable for sterile environments.

POLYTRON® - PT 2500 E Stand Dispersion Unit (Ecoline)

The PT2500 E is the ideal solution for cost-conscious laboratories. It is able to perform homogenizations with volumes from 0.05 to 2500 ml. The electronic control system continuously monitors the speed and automatically adjusts it, keeping it constant with changing viscosity. The speed is easily seen on the large digital display.

Aggregates with a variety of styles and diameters are available to provide optimum particle size reduction when using this drive. There are many different styles of aggregates available from 3mm in diameter for volumes down to 0.01 mL to 12mm for volumes up to 250mL. If cross contamination from sample to sample is a concern, we offer single use synthetic aggregates in 7 and 12 mm diameters. One of the more recent additions to our line is the PT-DA 20/2 X EC aggregate which was specifically designed for homogenizing tablets.

Highlights

  • Filling volumes 0.05 ml to 2.5 l
  • Laboratory instrument for budget conscious users
  • Sample operation with on/off and speed control
  • Intelligent variable speed control to protect the motor for the longest period of time
  • Leading speed stability even with changing viscosity
  • EasyClean system makes cleaning very efficient

POLYTRON® - PT 10/35 GT Powerful Stand Dispersing Unit (Ecoline)

The PT 10-35 GT with its 1200 watt motor can be used for applications with operating volumes up to 10 liters. More than 30 dispersion aggregates with different geometries, designs, sizes, materials and coatings are available for selection which tremendously expands the number of possible applications of this unit. The electronic control system continuously compares the preselected rpm speed with the actual speed and adjusts it so that the speed remains constant even as the viscosity increases. More than 30 dispersion aggregates with different geometries, designs, sizes, materials and coatings are available for selection.

Highlights

  • Filling volumes 0.1l to 10 l
  • Powerful disperser at fair price point
  • Simple operation with on/off and speed control
  • Intelligent variable speed control to protect motor for longest possible life
  • Leading speed stability even with changing viscosity
  • EasyClean system makes cleaning very efficient
  • Click&Go coupling for fast tool changes

MEGATRON® - MT 3100 S2
The next generation: New Inline Homogenizing

When testing and optimizing formulas, high process safety is paramount. This system enables processing of complex material systems with absolutely minimal loss of mass and minimal energy. This miniature format production system delivers efficent, replicable results like those of our inline machines used in large volume production.

Highlights

  • Inline tool for pilot / upscale work at up to 11 l/min speed
  • Used for small scale inline production or scale up
  • Provides replicable results to production tools
  • Recirculation mode to ensure maximum particle consistency and batch uniformity
  • Quick couplings for fast setup and changeover
  • Large selection of processing tools

MEGATRON® - MT SV
In-Line Dispersers for Sterile Environments

The sterile manufacture of pharma, cosmetic, food and life science requires dispersing technology especially designed for process safety and quality. Among these features are high-grade stainless steel materials, approved static and dynamic sealing systems, designs far-reaching free of dead space and with fine surface finishes, SIP and CIP cleaning possibility, and compliance with the required cleanroom classification.

Highlights

  • Inline disperser for up to 25,000 l/h (for water)
  • Suitable for sterile pharma production
  • Seamless integration into high throughput production environments
  • Highest grade materials, approved static and dynamic seal systems
  • Working chambers for CIP / SIP etc
  • Clean room compatible
Production Technologies
ConcentrationHomogenisationIsolate PurificationDecarboxylationPlant MillingPlant DryingEthanol EvaporationExtractionPreparationFiltrationTrypene ExtractionFreeze DryingConfiner Integrity TestingWinterisation & Filtration
Cannabis Analysis
Sample PreparationMoisture TestingTotal Organic Carbon AnalysisStability TestingHeavy Metal Analysis
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