Freeze Drying


Bench Top Lyophilizers BenchTop Pro

SP Scientific benchTop freeze dryers have been designed to meet the needs of the most demanding research laboratories. Each system can be configured to meet your present and future needs. Condenser refrigeration packages of -55°C, -75°C, -85°C and -105°C can meet the demands of both aqueous or aqueous-solvent based formulations.

Hightlights

  • Compact bench-top design
  • Avilable in 3, 8 and 9 liter configurations
  • Direct chamber, flask and/or rack drying capabilities
  • Programmable PLC-based Omnitronics controller with unique functions such as email alerts
  • One touch system auto-start and one touch auto-stop
  • Remote user and technician access unmatched system support
  • Unique self test function to assist with trouble shooting

BenchTop Lyophilizers - AdVantage Pro

This is the smallest process development of small pilot batch freeze dryer on the market. It offers similar high-performance technology as much larger floor-standing models. The shelves are actively cooled for on-shelf freezing of your sample enabling true one-process drying. it offers the convenience of a tray dryer in a benchTop unit.

The fully programmable touchscreen Intellitronics Controller offers users many unique functions such as Ethernet remote access and email communications. Giving you the capability of being able to monitor your cycles from anywhere and receive email notifications of important events.

Performance Features

  • Convenience of a tray dryer in a benchtop unit
  • Actively cooled and heated shelves for true one-process drying
  • Intellitronics controler with a full-color touch screen-display
  • Optional pneumatic stoppering system available to stopper vials
  • Six-liter ice condensing capacity

Process Development Freeze Dryer - LyoStar3

The LyoStar3 is designed to meet the highest needs of pharmaceutical process development professionals. It provides unmatched capabilities in terms of performance, process accuracy, reliability, and unique ease-of-use features, that are unmatched by any other freeze dryer.

The LyoStar features Type T thermocouple-controlled shelf temperature accuracy of +/- 0.5°C or better and vacuum control within 0.1% of set-point.

It's robust 5.5 hp cascade refrigeration system enables shelf to pull down from ambient to -40°C in less than 25 minutes, and the ultra-reliable scroll compressors feature just 3 moving parts.

LyoStar3 is available with our unique and patented Praxair ControlLyo Nucleation on Demand Technology. ControLyo Nucleation uses a patented depressurisation method to force simultaneous product nucleation. It is currently the only production validated controlled ice nucleation technology on the market.

Performance Features

  • Convenience of a tray dryer in a benchtop unit
  • Actively cooled and heated shelves for true one-process drying
  • Intellitronics controler with a full-color touch screen-display
  • Optional pneumatic stoppering system available to stopper vials
  • Six-liter ice condensing capacity

SMART Freeze Drying

SP Scientifics' patented SMART technology puts the experience of the world's top lyophilization experts into an easy to use cycle development tool. SMARTS eliminates the common trial-and-error approach and replaces it with reproducible measurements and auto-tuning. Case studies have shown development cost and time savings as high as 78%.

LyoFlux

This is an innovative line-of-sight tunable diode laser system for in-situ real-time measurement gives a better understanding of drying rates and allows precise process endpoint determination.


Production Freeze Drying

SP Scientific is your one-stop-shop for clinical and production freeze dryers. They offer a wide range of production tools to suit every application. SP Scientific offers patented technology including their ControLyo Nucleation.

With the recent acquisition of PennTech SP can now also offer a full range of pharmaceutical automation technologies including automatic freeze drying loading and unloading, vial washing and much more.

Freeze Drying Options available include

  • Single chamber and double chamber design
  • Bulk and stoppering
  • 10 kg to 1,500 kg batch capacity
  • Steam sterilisable (SIP) and clean in place (CIP)
  • Auto-locking SIP doors
  • Redundant system components

Freeze Drying Options available include

  • Batch reporting (CFR 21 P122 compliant)
  • Allen Bradley and Siemens controllers
  • Patented ControLyo Nucleation
  • Aseptic production system
  • Unique PAT tools including wireless temperature sensor, TDLAS laser moisture measurement and many more

Hybrid Pumping Unit - RC 6

The RC 6 chemistry-HYBRID pump is a combination of a two-stage rotary vane pump and a two-stage chemistry diaphragm pump for optimized corrosion resistance. The diaphragm pump maintains the oil reservoir under vacuum in order to keep the partial pressure of solvent vapors at levels below their condensation points. Therefore the RC 6 chemistry-HYBRID pump has a much higher solvent vapor pumping capability and resistance to aggressive gases than conventional rotary vane pumps.

Highlights

  • Oil changes typically reduced 90% or more
  • Reduced internal corrosion, even when working with corrosive vapors.
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